The Ghrelin System
The ghrelin story started more than 30 years ago with the discovery of synthetic GH secretagogues. Only in 1999 was ghrelin, a natural GH-releasing peptide, discovered. Ghrelin, however, is much more than simply a natural GH secretagogue. In fact, this hormone is one of the most important factors known for regulating appetite and energy expenditure. Furthermore, ghrelin is the [...]
[lire le résumé du livre]
Auteur : A. BENSO , F.F.CASANUEVA , E.GHIGO , R.GRANATA
Editeur : Karger
Collection : Endocrine Development - 25
Date parution : 05/2013Bilingue : Français | Anglais
CB Google/Apple Pay, Chèque, Virement
Quel est le sujet du livre "The Ghrelin System"
The ghrelin story started more than 30 years ago with the discovery of synthetic GH secretagogues.
Only in 1999 was ghrelin, a natural GH-releasing peptide, discovered. Ghrelin, however, is much more than simply a natural GH secretagogue. In fact, this hormone is one of the most important factors known for regulating appetite and energy expenditure. Furthermore, ghrelin is the trigger for other neuroendocrine, metabolic and nonendocrine actions.
This book, written by researchers who provided the major contributions to our carrent knowledge of this complex system, gives a comprehensive overview of the recent advances in ghrelin research. The hormone's influence on the cardiovascular, metabolic and gastroenteropancreatic system, hypothalamus-pituitary-adrenal axis, prolactin secretion, thyroid axis, gonadal axis as well as on behavior is discussed in detail. Furthermore, the clinicat perspectives for ghrelin-derived therapeutic products are presented.
Illustrating the tight inter-relationship between endocrinology, metabolism, cardiovascular disease and interna) medicine, this book is essential reading for all scientiste interested in appetite control, body weight and energy expenditure, as well as diabetes mellitus and neuroendocrinology.
Sommaire et contenu du livre "The Ghrelin System"
ContentsVII Preface
Benso, A (Turin); Casanueva, F.F. (Santiago de Compostela); Ghigo, E.; Granata, R (Turin)
1 Ghrelin Discovery: A Decade After
Kojima, M. (Kurume); Kangawa, K. (Osaka)
S The Ghrelin Receptors (GHS-Rl a and GHS-Rl b)
Albarran-Zeckler, RG.; Smith, RG. (Jupiter, Fla.)
16 Discovery of Ghrelin O-Acyltransferase
Mohan, H.; Unniappan, S. (Saskatoon, SAS)
2S Genetics of the Ghrelin System
Gueorguiev, M.; Korbonits, M. (London)
41 Ghrelin and the Gut
Peeters, T.L. (Leuven)
49 Ghrelin as a GH-Releasing Factor
Carreira, M.C; Crujeiras, A.B. (Santiago de Compostela); Andrade, S. (Santiago de
Compostela/Porto); Monteiro, M.P; Casanueva, FJ. (Santiago de Compostela)
S9 Other than Growth Hormone Neuroendocrine Actions of Ghrelin
Benso, A; Calvi, E.; Gramaglia, E.; Olivetti, 1.; Tomelini, M.; Ghigo, E.; Broglio, F (Turin)
69 Ghrelin, the Gonadal Axis and the Onset of Puberty
Tena-Sempere, M. (C6rdoba)
83 Ghrelin and the Cardiovascular System
Isgaard, J. (Gothenburg)
91 Ghrelin -A Key Pleiotropic Hormone-Regulating Systemic Energy Metabolism
Müller, T.D.; Tschbp, M.H. (Munich)
101 Ghrelin, Reward and Motivation
Menzies, J.RW (Edinburgh); Skibicka, K.P (Gothenburg); Leng, G. (Edinburgh);
Dickson, S.L. (Gothenburg)
112 Des-Acyl Ghrelin: A Metabolically Active Peptide
Delhanty, PJ.; Neggers, S.J.; van der Lely, AJ. (Rotterdam)
122 Ghrelin and Tumors
Papotti, M.; Duregon, E.; Volante, M. (Orbassano, Turin)
13S Ghrelin Function in Insulin Release and Glucose Metabolism
Dezaki, K. (Shimotsuke)
144 Products of the Ghrelin Gene, the Pancreatic J3-Cell and the Adipocyte
Granata, R.; Ghigo, E. (Turin)
157 Clinical Perspectives for Ghrelin-Derived Therapeutic Products
Allas, 5.; Abribat, T (Ecully)
167 Author Index 168 Subject Index
PDF 0 Ko)
