Leptospirosis and the Kidney
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Current knowledge and new perspectives for future research.Leptospirosis is the most common zoonotic disease worldwide, involving at least 1 million patients annually. Kidney is the preferential colonization site where Leptospira accumulates during systemic infection, primarily in the interstitium and in renal tubule epithelial cells. In acute [...]
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Auteur : C.W. YANG , M.J. PAN , H.Y. YANG
Editeur : Karger
Collection : Translational Reseach in Biomedicine - 7
Date parution : 09/2019Bilingue : Français | Anglais
Reliure :
Relié
Nbr de pages :
106
Dimension :
19.4 x 26 cm
ISBN 10 :
3318065390
ISBN 13 :
9783318065398
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Quel est le sujet du livre "Leptospirosis and the Kidney"
Current knowledge and new perspectives for future research.
Leptospirosis is the most common zoonotic disease worldwide, involving at least 1 million patients annually. Kidney is the preferential colonization site where Leptospira accumulates during systemic infection, primarily in the interstitium and in renal tubule epithelial cells. In acute kidney injury (AKI), the main histological findings are acute tubulo-interstitial nephritis and acute tubular necrosis, characterized by hypokalemia and non-oliguria. The injury caused by leptospira outer membrane protein components involves innate immunity Toll-like receptor pathways and activation of complement and immune cascades in the kidney, together with extracellular matrix accumulation when the kidney infection progress to chronic kidney disease (CKD). Significantly, recent studies indicate that leptospira may induce CKD in humans either with AKI-CKD continuum or subclinical leptospira infection leading to CKD. Leptospirosis kidney disease thus represents a newly discovered and previously overlooked area requiring intensive medical and public health attention and investigation. In this book, leading experts in the field contribute their cutting-edge clinical and research experiences for the understanding of leptospirosis kidney disease.
The outstanding feature of this publication is emphasizing kidney injury and disease induced by leptospirosis, an underestimated infection involving multiple organs. The book contributes information on current knowledge of leptospirosis kidney disease and a new perspective for future research.
En suivant ce lien, retrouvez tous les livres dans la spécialité Néphrologie.The outstanding feature of this publication is emphasizing kidney injury and disease induced by leptospirosis, an underestimated infection involving multiple organs. The book contributes information on current knowledge of leptospirosis kidney disease and a new perspective for future research.
Sommaire et contenu du livre "Leptospirosis and the Kidney"
PreliminariesTransl Res Biomed 2019;7:– (DOI:10.1159/000500374)
Free Access
VII
Foreword
Yang C-W, Pan M-J, Yang H-Y (eds): Leptospirosis and the Kidney. Transl Res Biomed. Basel, Karger, 2019, vol 7, pp VII–VIII (DOI: 10.1159/000502185) (DOI:10.1159/000502185)
IX
Preface
Yang C.-W. · Pan M.-J. · Yang H.-Y.
Yang C-W, Pan M-J, Yang H-Y (eds): Leptospirosis and the Kidney. Transl Res Biomed. Basel, Karger, 2019, vol 7, pp IX–X (DOI: 10.1159/000500375) (DOI:10.1159/000500375)
1
Leptospirosis and the Kidney: An Overview
Srisawat N. · Sitprija V.
Yang C-W, Pan M-J, Yang H-Y (eds): Leptospirosis and the Kidney. Transl Res Biomed. Basel, Karger, 2019, vol 7, pp 1–9 (DOI: 10.1159/000500376) (DOI:10.1159/000500376)
10
Pathophysiology of Leptospirosis Kidney Disease
Wu M.-Y. · Wu M.-S.
Yang C-W, Pan M-J, Yang H-Y (eds): Leptospirosis and the Kidney. Transl Res Biomed. Basel, Karger, 2019, vol 7, pp 10–19 (DOI: 10.1159/000500378) (DOI:10.1159/000500378)
20
Leptospirosis-Associated Acute Kidney Injury
Lin C.-Y.
Yang C-W, Pan M-J, Yang H-Y (eds): Leptospirosis and the Kidney. Transl Res Biomed. Basel, Karger, 2019, vol 7, pp 20–26 (DOI: 10.1159/000500379) (DOI:10.1159/000500379)
27
Leptospirosis and Chronic Kidney Disease
Yang H.-Y. · Chang C.-H. · Yang C.-W.
Yang C-W, Pan M-J, Yang H-Y (eds): Leptospirosis and the Kidney. Transl Res Biomed. Basel, Karger, 2019, vol 7, pp 27–36 (DOI: 10.1159/000500380) (DOI:10.1159/000500380)
37
Detection and Treatment of Leptospirosis Kidney Disease
Chiu S.-H. · Pan M.-J.
Yang C-W, Pan M-J, Yang H-Y (eds): Leptospirosis and the Kidney. Transl Res Biomed. Basel, Karger, 2019, vol 7, pp 37–46 (DOI: 10.1159/000500381) (DOI:10.1159/000500381)
47
Innate Immunity and Kidney Injury in Leptospirosis
Hung C.-C.
Yang C-W, Pan M-J, Yang H-Y (eds): Leptospirosis and the Kidney. Transl Res Biomed. Basel, Karger, 2019, vol 7, pp 47–56 (DOI: 10.1159/000500382) (DOI:10.1159/000500382)
57
Leptospirosis and Kidney Fibrosis
Tian Y.-C.
Yang C-W, Pan M-J, Yang H-Y (eds): Leptospirosis and the Kidney. Transl Res Biomed. Basel, Karger, 2019, vol 7, pp 57–64 (DOI: 10.1159/000500387) (DOI:10.1159/000500387)
65
Murine Models for Leptospirosis Kidney Disease
Werts C.
Yang C-W, Pan M-J, Yang H-Y (eds): Leptospirosis and the Kidney. Transl Res Biomed. Basel, Karger, 2019, vol 7, pp 65–75 (DOI: 10.1159/000500388) (DOI:10.1159/000500388)
76
Zebrafish Model for Leptospirosis Kidney Disease
Chang M.-Y. · Cheng Y.-C.
Yang C-W, Pan M-J, Yang H-Y (eds): Leptospirosis and the Kidney. Transl Res Biomed. Basel, Karger, 2019, vol 7, pp 76–81 (DOI: 10.1159/000500389) (DOI:10.1159/000500389)
82
Structural and Functional Biology Approaches of Leptospirosis Kidney Disease
Hsu S.-H. · Yang C.-W.
Yang C-W, Pan M-J, Yang H-Y (eds): Leptospirosis and the Kidney. Transl Res Biomed. Basel, Karger, 2019, vol 7, pp 82–93 (DOI: 10.1159/000500390) (DOI:10.1159/000500390)
94
Systems Biology Approach to Understanding Leptospirosis Kidney Disease
Chou L.-F. · Yang C.-W.
Yang C-W, Pan M-J, Yang H-Y (eds): Leptospirosis and the Kidney. Transl Res Biomed. Basel, Karger, 2019, vol 7, pp 94–101 (DOI: 10.1159/000500391) (DOI:10.1159/000500391)
102
Author Index
Yang C-W, Pan M-J, Yang H-Y (eds): Leptospirosis and the Kidney. Transl Res Biomed. Basel, Karger, 2019, vol 7, pp 102 (DOI: 10.1159/000500867) (DOI:10.1159/000500867)
Free Access
103
Subject Index
Yang C-W, Pan M-J, Yang H-Y (eds): Leptospirosis and the Kidney. Transl Res Biomed. Basel, Karger, 2019, vol 7, pp 103–105 (DOI: 10.1159/000500868) (DOI:10.1159/000500868)
Free Access
